Picture this: it’s the middle of the week, you’re dog-tired, and cooking even the most basic meal feels like a chore. We’ve all been there—when the days are long and the week has been nothing but a blur of work and family activities, standing up to prepare a meal is the last thing on your mind. In these moments, you need a pasta casserole. Creamy, melty, filling, and warm, it’s the perfect dish to enjoy when cooking isn’t on the agenda.
Casseroles are rooted in American culture. The easy-to-make dish was a staple on the table for many busy families for good reason. Not only are they easy to make and filling, but they feed a crowd, often giving you leftovers for days. Beyond that, most casserole dishes are fitting for picky palates, making them perfect for a large family with different tastes.
Most casseroles are made from five key ingredients: pasta, a protein, vegetables, cheese, and sauce. Whether you choose to go spicy and bold with a tomato sauce or savory with a cream-based sauce, the possibilities are endless. To get you started, we’ve gathered five interesting pasta casseroles to add to your recipe Rolodex.

Lasagna Casserole
Ingredients
- 1 pound ground beef
- 1/4 cup chopped onion
- 1 pound pasta shells; cooked medium
- 4 cups shredded part-skim mozzarella cheese
- 3 cups cottage cheese
- 2 large eggs
- 1/3 cup grated Parmesan cheese
- 1/2 teaspoon salt
- 1/2 teaspoon pepper
- 2 tablespoons dried parsley flakes
- 1 24-ounce jar of pasta sauce
Instructions
- Cook ground beef and onion in a skillet and season to taste with salt and pepper.
- Add the cooked pasta, eggs, cottage cheese, Parmesan cheese, 3 cups of mozzarella cheese, parsley, and pepper to a large bowl and gently stir to mix.
- Transfer pasta mixture to a baking dish and top with ground beef and pasta sauce.
- Cover with aluminum foil and bake for at least 45 minutes.
- Remove the foil and sprinkle with remaining mozzarella chesse.
- Bake uncovered, until cheese is melted.
- Cool for 10 minutes, serve, and enjoy.

Turkey Tetrazzini
Ingredients
- 1 box uncooked spaghetti
- 2 cups chopped cooked turkey (white and dark meat)
- 5 tablespoons unsalted butter
- 1 cup finely chopped yellow onion
- 8 ounces sliced button mushrooms
- 2 medium garlic cloves
- 1/3 cup dry sherry
- 1/4 cup all-purpose flour
- 2 cups chicken broth
- 3/4 cup half-and-half
- 1 can cream of celery soup
- 1/2 cup sour cream
- 1/2 teaspoon salt
- 1/2 teaspoon black pepper
- 6 ounces shredded mozzarella
- 2 ounces grated Parmesan cheese
- 1 1/2 cups frozen peas
- Chopped parsley
Instructions
- Cook the spaghetti.
- Melt butter in a large skillet, then add the chopped onion and mushrooms and cook until tender.
- Mince garlic and stir into the skillet mixture.
- Stir in sherry and continue cooking until reduced.
- Stir in flower until sauce begins to thicken.
- Reduce heat under the skillet and gradually stir in chicken broth and half-and-half.
- Add cream of celery soup, sour cream, parsley, salt, and pepper and cook until sauce is smooth and simmering.
- Remove skillet from heat and add turkey, 1 cup of the mozzarella cheese, and 1/4 cup of the Parmesan cheese until everything is well mixed.
- Gently fold in the spaghetti and add peas.
- Transfer pasta mixture to a baking dish and top with remaining cheese.
- Bake until golden brown.
- Let cool, then garnish with parsley and enjoy.

Chicken Bacon Ranch Casserole
Ingredients
- 1 package uncooked spiral pasta
- 1-1/2 cups milk
- 1/2 cup ranch salad dressing
- 1 package ranch salad dressing mix
- 1 package cream cheese, cubed
- 2 cups cooked chicken
- 8 bacon strips, cooked and crumbled
- 2 cups shredded Colby cheese
- Sliced green onions
Instructions
- Cook the pasta then drain and transfer to a large mixing bowl.
- Add milk, ranch salad dressing, and ranch salad dressing mix to the pan and stir until combined.
- Stir in cream cheese and cook over medium heat until melted.
- Pour mixture over pasta.
- Stir in chicken, bacon, and 1 cup Colby cheese.
- Transfer pasta mixture to a baking dish.
- Top with remaining 1 cup Colby cheese.
- Bake, uncovered, until cheese is melted.
- Remove and let cool.
- Top with green onion, serve, and enjoy.

Pulled Pork Mac And Cheese
Ingredients
- 1 box uncooked elbow pasta
- 1/2 cup unsalted butter
- 1 1/2 cups finely chopped onion
- 1/4 cup all-purpose flour
- 3 1/2 cups milk
- 2 teaspoon Dijon mustard
- 1 teaspoon garlic powder
- 1/2 teaspoon pepper
- 2 cups shredded extra-sharp Cheddar cheese
- 2 cups shredded Colby-Jack cheese
- 2 1/2 cups sauceless shredded smoked pork
- 1 cup panko
- 1/4 cup sliced scallions
- Barbecue sauce
Instructions
- Cook the pasta
- Melt 6 tablespoons of butter in a large Dutch oven.
- Add onion and cook until soft.
- Stir in flour.
- Gradually stir in milk, mustard, garlic powder, and pepper until mixture thickens.
- Remove Dutch oven from heat and gradually stir in cheddar and Colby-Jack cheeses.
- Add pork and pasta to cheese mixture and stir.
- Transfer pasta mixture to a baking dish.
- Melt remaining butter in the microwave and stir in panko until combined.
- Sprinkle on top of pasta mixture.
- Bake for about 30 minutes until mixture is brown and bubbly.
- Remove from oven and let cool for 10 minutes.
- Top with scallions and barbecue sauce, serve and enjoy.

Tuna Casserole
Ingredients
- 1 package wide egg noodles
- 3 tablespoons unsalted butter, divided
- 1 yellow onion, diced
- 2 tablespoons all-purpose flour
- 2 cups milk
- 1 teaspoon Dijon mustard
- 1/2 teaspoon salt
- 1/4 teaspoon pepper
- 1/2 cup and 2 tablespoons grated Parmesan cheese
- 2 cans chunk light tuna, drained
- 1 cup frozen peas
- 16 butter crackers
- 1/2 teaspoon garlic powder
Instructions
- Cook the pasta.
- Melt 2 tablespoons of butter in large skillet.
- Add onion and cook until soft.
- Stir in flour.
- Gradually stir in milk and reduce heat to a simmer, cooking until mixture has thickened.
- Remove skillet from heat and stir in Dijon mustard, salt, and pepper.
- Stir in 1/2 cup Parmesan cheese.
- Stir in tuna, frozen peas, and noodles.
- Transfer pasta mixture to a baking dish.
- Bake for 15 minutes.
- Melt remaining butter in the microwave and stir in crushed crackers, remaining 2 tablespoons Parmesan cheese and garlic powder.
- Remove casserole from oven and top with cracker mixture, then bake for 7 minutes until topping is browned.
- Let cool for 5 minutes, serve, and enjoy.
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